A surprising discovery suggests that some early signs of Alzheimer’s disease may begin outside the brain. Using miniature laboratory systems made from human cells, scientists found that genetic mutations associated with inherited Alzheimer’s can disrupt nerve-to-muscle connections without any involvement from the brain or spinal cord. This could help explain why some patients experience changes in balance, walking, and coordination long before memory problems develop.

Scientists have uncovered a hidden gut-to-brain dopamine pathway that helps explain why bitter coffee and other initially unpleasant flavors can become favorites over time. The discovery reveals how the brain learns to crave certain foods and could eventually lead to new ways of reshaping eating habits and food preferences.

CERN scientists have finally found evidence of a particle decay so rare that it happens only once in roughly 10 billion decays, ending a search spanning more than 40 years. The breakthrough could help physicists uncover hidden particles and forces that lie beyond the reach of today's most powerful accelerators.

Scientists have discovered that pantethine, a readily available vitamin B5 derivative, can calm overactive immune cells and may help fight psoriasis. The supplement prevented psoriasis in mice and showed promising results in a small human trial, revealing an unexpected connection between cholesterol and autoimmune inflammation.

NASA has revealed an accelerated plan to land astronauts on the Moon in 2028, with SpaceX and Blue Origin developing competing lunar landers and a crucial orbital test scheduled for 2027. Faster rocket preparations, new lightweight spacesuits, and redesigned missions could help pave the way for a permanent lunar presence and future human exploration of Mars.

For the first time, a robot has autonomously built part of a structure in space, demonstrating a breakthrough that could fundamentally change space exploration. The technology could one day allow scientists to construct enormous telescopes, communications antennas, and solar power stations in orbit, far beyond the size limits of today's rockets.

A massive study of more than 120,000 older adults suggests that common osteoporosis drugs may reduce the risk of Alzheimer’s disease and other dementias by up to 24%. The surprising findings raise the possibility that medications already used to strengthen bones could also help protect the aging brain.

The Shroud of Turin, one of history's most mysterious religious artifacts, is yielding surprising new clues through DNA analysis. Scientists have uncovered a complex mixture of biological traces that may reveal more about the cloth's past and the environments it encountered. The findings offer a fresh scientific perspective on a centuries-old mystery that continues to spark fascination and debate.

After more than 35 years of research, scientists have uncovered surprising clues about what really drives Lyme disease risk. Contrary to longstanding assumptions, deer populations appear less important than mice, which can fuel a 40% increase in tick numbers the following year. Even acorn production can predict tick population surges two years in advance, while extreme temperatures may be far less deadly to ticks than scientists once believed.

Scientists have observed a bizarre quantum state of matter that combines the structure of a crystal with the frictionless flow of a liquid, all at room temperature. The breakthrough overturns a major practical limitation of exotic quantum experiments and could help bring powerful new light-based computing and sensing technologies closer to reality.

Scientists have discovered that gut bacteria can feed on the protective mucus lining your intestines, producing potentially harmful compounds, but fiber helps keep this activity in check. Overlooked proteins in plant foods also help shift gut bacteria toward producing beneficial substances, revealing a surprising new reason plant-based diets may be good for you.

A surprising new study from UCLA suggests that a naturally occurring molecule could help breast cancer survivors overcome the frustrating brain fog and exhaustion that can linger long after treatment ends. Researchers found that women taking an oxaloacetate supplement for eight weeks experienced substantial improvements in memory, concentration, mental clarity, and fatigue.

Scientists have discovered that a buildup of a protein called Miro1 may be a hidden driver of insulin resistance in Type 2 diabetes, with preclinical experiments showing that removing it restores the muscles’ response to insulin. Exercise was also found to lower Miro1 levels in people with diabetes, revealing a potential new pathway for treating the disease.

A remarkable fossil discovery in Colombia is challenging how scientists understand major evolutionary changes in Earth's history. Researchers uncovered an incredibly diverse ancient marine ecosystem where giant reptiles, sharks, and other creatures thrived as older evolutionary groups approached extinction and newer ones emerged. They call this previously unrecognized pattern a "Biotic Inflection," suggesting that major transformations in life can occur without mass extinctions.

Scientists have discovered that the stickiness of underwater “marine snow” plays a surprisingly important role in how much carbon reaches the deep ocean. Gooier particles resist bacterial breakdown and can transport more than six times as much carbon to the depths, revealing an unexpected connection between ocean slime and Earth's climate.

Researchers have discovered a stunning new species of tiny orange-patterned fish in the Brazilian Amazon, but its survival may already be at risk. Named Laimosemion laranja, the brilliantly colored killifish measures less than three centimeters long and was found in just three small forest pools. Its extremely limited habitat is threatened by mining, deforestation, pollution, and expanding development.

More than a century after Einstein revolutionized our understanding of gravity, scientists have uncovered a surprising new phenomenon hidden within his equations. Researchers at Columbia University and Universidad Adolfo Ibáñez have identified a theoretical process called "gravitational reconnection," in which structures within gravitational fields can break apart and reconnect, transferring energy into matter.

Scientists at UC San Francisco have developed a powerful new cancer therapy that remains inactive until it reaches the brain, where it switches on to attack deadly tumors. The engineered immune cells, called B-SYNC CAR-T cells, completely eliminated diffuse midline glioma (DMG), an aggressive childhood brain cancer that is almost always fatal within a year, in two mouse models.

Scientists have discovered a surprising quantum limit that prevents electrons from being tracked with unlimited precision in both space and time. The breakthrough could pave the way for manipulating chemical reactions and developing electronics hundreds of thousands of times faster than today's technology.

A nuclear explosion might save Earth from a deadly asteroid, but new research suggests that hitting the wrong side could make the difference between success and disaster. Scientists found that an asteroid's irregular shape can dramatically affect how it responds to an X-ray blast, with deflection effectiveness varying nearly fivefold depending on the angle.