Scientists discovered that lowered brain energy signaling in the hippocampus can lead to both depression- and anxiety-like behaviors in mice. Stress reduced ATP, a molecule important for cell energy and communication. Altering a protein called connexin 43, which helps release ATP, caused similar symptoms even without stress. Restoring this protein improved mood-related behavior.

Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective effect.

Beneath the waters off Papua New Guinea lies an extraordinary deep-sea environment where scorching hydrothermal vents and cool methane seeps coexist side by side — a pairing never before seen. This unusual chemistry fuels a vibrant oasis teeming with mussels, tube worms, shrimp, and even purple sea cucumbers, many of which may be unknown to science. The rocks themselves shimmer with traces of gold, silver, and other metals deposited by past volcanic activity.

An immense pocket of hot rock deep beneath the Appalachians may be a wandering relic of the breakup between Greenland and North America 80 million years ago. Researchers suggest this slow-moving “mantle wave” drifted over 1,800 km to reach its current position, gradually reshaping the continent from below and even helping prop up the Appalachian Mountains long after tectonic activity at the surface ceased.

Rerouted shipping during Red Sea conflicts accidentally created a massive real-world experiment, letting scientists study how new low-sulfur marine fuels affect cloud formation. The sudden surge of ships around the Cape of Good Hope revealed that cleaner fuels dramatically weaken the ability of ship emissions to seed bright, reflective clouds—cutting this cloud-boosting effect by about two-thirds.

Personalized algorithms may quietly sabotage how people learn, nudging them into narrow tunnels of information even when they start with zero prior knowledge. In the study, participants using algorithm-curated clues explored less, absorbed a distorted version of the truth, and became oddly confident in their wrong conclusions. The research suggests that this kind of digital steering doesn’t just shape opinions—it can reshape the very foundation of what someone believes they understand.

Researchers studying Yellowstone’s depths discovered that small earthquakes can recharge underground microbial life. The quakes exposed new rock and fluids, creating bursts of chemical energy that microbes can use. Both the water chemistry and the microbial communities shifted dramatically in response. This dynamic may help explain how life survives in deep, dark environments.

A horned native bee dubbed Megachile lucifer has been discovered in Western Australia’s Goldfields. Identified while surveying a rare wildflower, the species stood out with its unusual “devilish” facial horns. DNA testing confirmed it was previously unknown. The find exposes major gaps in bee surveying, especially in areas under pressure from mining.

Using a precisely aligned pair of laser beams, scientists can now hold a single aerosol particle in place and monitor how it charges up. The particle’s glow signals each step in its changing electrical state, revealing how electrons are kicked away and how the particle sometimes releases sudden bursts of charge. These behaviors mirror what may be happening inside storm clouds. The technique could help explain how lightning gets its initial spark.

Moss spores survived an extended stay on the outside of the ISS and remained capable of germinating once back on Earth. Their resilience to vacuum, extreme temperatures, and UV radiation surprised the researchers who expected them to perish. The spores' natural protective coat likely played a key role in shielding them. The study hints at the potential for simple plants to support agriculture beyond our planet.

Scientists have found that a mutation tied to Alzheimer’s disrupts the production and quality of exosomes—tiny cell-made communication packets. Cells with the defective SORLA protein generate fewer exosomes and ones far less able to support nearby brain cells. This weakness may be a key driver of Alzheimer’s development. The research points to new treatment strategies that enhance or restore exosome function.

Scientists found that high-flavanol foods can prevent the decline in blood vessel function that occurs after prolonged sitting. Even physically fit men weren’t protected unless they had consumed flavanols beforehand. A cocoa drink rich in these compounds kept arteries functioning normally. Everyday foods like berries, apples, tea, and certain cocoa products could offer a simple way to protect long-term vascular health.

Ribosomes don’t just make proteins—they can sense when something’s wrong. When they collide, they send out stress signals that activate a molecule called ZAK. Researchers uncovered how ZAK recognizes these collisions and turns them into protective responses. The discovery shows how cells quickly spot trouble.

Europe is investing in a coordinated effort to develop high-power optical vortex technologies and train new specialists in the field. The HiPOVor network unites academia and industry to advance applications ranging from material processing to environmentally friendly photonic systems.

Participants lost more weight on a low-fat vegan diet than on the Mediterranean diet, largely due to eliminating animal foods and reducing oils and nuts. Increased intake of plant foods, even “unhealthy” ones, was strongly associated with greater weight loss.

Scientists are uncovering what makes some carcinomas so resistant: their ability to change identity. Two new studies reveal crucial proteins and structures that could become targets for future therapies. These discoveries deepen understanding of how tumors reprogram themselves and point toward highly specific treatments. The work raises hopes for safer, more selective cancer drugs.

A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering repair within seconds. The mechanism works in both injury and disease models. The discovery could inspire new treatments for muscle recovery and degeneration.

Hypertension begins harming the brain surprisingly early, even before measurable blood pressure increases. Key cells related to blood vessels, signaling, and myelin maintenance begin aging prematurely and malfunctioning. These disruptions resemble early patterns seen in cognitive decline and Alzheimer’s. Encouragingly, losartan reversed some of this early damage in mice.

Scientists have uncovered how leukemia cells manage to escape one of the most commonly used treatments. Over time, these cancer cells subtly change the shape of their mitochondria to avoid dying when the drug tries to kill them. By identifying the protein that controls this shape-shifting, researchers were able to block it in mice, making the treatment powerful again and dramatically extending survival.

Sargassum seaweed is creating major new obstacles for sea turtle hatchlings, drastically slowing their crawl to the ocean and increasing their risk from predators and heat. Despite the physical challenge, their energy stores stay stable, suggesting the real danger lies in the delay itself.