A next-generation drug tested in yeast was found to extend lifespan and slow aging by influencing a major growth-control pathway. Researchers also uncovered an unexpected role for agmatinases, enzymes that help keep this pathway in balance. Diet and gut microbes may affect aging more than expected because they produce the metabolites involved.

Regular consumption of polyphenol-rich foods like tea, coffee, berries, nuts, and whole grains may significantly support long-term heart health. A decade-long study of more than 3,100 adults found that those who consistently ate polyphenol-packed diets had healthier blood pressure and cholesterol levels, as well as lower predicted cardiovascular risk.

A researcher from the University of Tokyo and a U.S.-based structural engineer developed a new computational form-finding method that could change how architects and engineers design lightweight and free-form structures covering large spaces. The technique specifically helps create gridshells, thin, curved surfaces whose members form a networked grid. The method makes use of NURBS surfaces, a widely used surface representation format in computer-aided design (CAD). It also drastically reduces computation cost — a task that previously took 90 hours on a high-end GPU completes in about 90 minutes on a standard CPU.

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages released by heart cells that naturally support healing after injury. By identifying and recreating the most powerful of these messages, the team developed a synthetic RNA molecule that boosts the body’s DNA-repair system, reduces scarring, and may improve recovery after heart attacks and other diseases.

A large study found that people with impaired kidneys tend to have higher Alzheimer’s biomarkers, yet they don’t face a higher overall risk of dementia. For those who already have elevated biomarkers, kidney problems may speed up when symptoms appear. The findings show that kidney health can change how Alzheimer’s blood tests are read. Doctors may need to consider both organs to get a clearer picture.

Kyushu University scientists have achieved a major leap in fuel cell technology by enabling efficient proton transport at just 300°C. Their scandium-doped oxide materials create a wide, soft pathway that lets protons move rapidly without clogging the crystal lattice. This solves a decades-old barrier in solid-oxide fuel cell development and could make hydrogen power far more affordable.

Researchers engineered a strained germanium layer on silicon that allows charge to move faster than in any silicon-compatible material to date. This record mobility could lead to chips that run cooler, faster, and with dramatically lower energy consumption. The discovery also enhances the prospects for silicon-based quantum devices.

A low-dose mix of zinc, serine, and branched-chain amino acids boosted neural function and social behavior in autism mouse models. The combination restored more typical synaptic protein patterns and reduced excessive amygdala activity. Individual supplements had no effect, showing that the nutrients must work together. The findings point toward a promising multi-nutrient strategy for influencing brain circuits involved in autism.

Fresh evidence suggests early Earth wasn’t locked under a rigid stagnant lid but was already experiencing intense subduction. Ancient melt inclusions and advanced simulations point to continents forming far earlier than expected. The findings overturn long-held assumptions about the planet’s infancy and reveal a surprisingly active Hadean world.

A network of powerful ground-based telescopes captured rare starspot-crossing events on TOI-3884b, revealing cooler patches on the star’s surface and rapid changes tied to its rotation. By combining multicolor transit observations with months of high-cadence brightness monitoring, researchers nailed down the star’s rotation period with impressive precision. These measurements allowed them to map the system’s geometry—and what they found was surprising: the planet's orbit is wildly tilted relative to the star’s spin.

Penn State researchers created seven new high-entropy oxides by removing oxygen during synthesis, enabling metals that normally destabilize to form rock-salt ceramics. Machine learning helped identify promising compositions, and advanced imaging confirmed their stability. The method offers a flexible framework for creating materials once thought impossible to synthesize.

Researchers found that people with anxiety disorders consistently show lower choline levels in key brain regions that regulate thinking and emotions. This biochemical difference may help explain why the brain reacts more intensely to stress in anxiety conditions. Scientists believe nutrition could play a role in restoring balance, though more research is needed. Many Americans already fall short of recommended choline intake, making diet a potential area of interest.

Researchers studying people with major psychiatric disorders found that drinking up to four cups of coffee a day is associated with longer telomeres. This suggests a potential slowing of biological aging by about five years. However, drinking five or more cups showed no benefit and may even contribute to cellular damage. Coffee’s antioxidant and anti-inflammatory properties may help explain the effect.

This year’s ozone hole over Antarctica ranked among the smallest since the early 1990s, reflecting steady progress from decades of global action under the Montreal Protocol. Declining chlorine levels and warmer stratospheric temperatures helped limit ozone destruction. Scientists say the layer remains on track to recover later this century.

Experiments reveal that pond frogs can eat highly venomous hornets without suffering noticeable damage, even after repeated stings. Most frogs successfully consumed hornets, including the notorious Asian giant hornet. This unusual resilience suggests that frogs may have evolved mechanisms to block the effects of venom. Their resistance could help scientists uncover new insights into pain and toxin tolerance.

Scientists have captured a never-before-seen, high-resolution look at influenza’s stealthy invasion of human cells, revealing that the cells aren’t just helpless victims. Using a groundbreaking imaging technique, researchers discovered that our cells actually reach out and “grab” the virus as it searches for the perfect entry point, surfing along the membrane.

For thirty years, SOHO has watched the Sun from a stable perch in space, revealing the inner workings of our star and surviving crises that nearly ended the mission. Its long-term observations uncovered a single global plasma conveyor belt inside the Sun, detailed how solar brightness subtly shifts over the solar cycle, and turned SOHO into an unexpected comet-hunting champion with more than 5,000 discoveries.

Earth’s orbit is getting crowded with broken satellites and leftover rocket parts. Researchers say the solution is to build spacecraft that can be repaired, reused, or recycled instead of abandoned. They also want new tools to collect old debris and new data systems that help prevent collisions. The goal is to make space exploration cleaner and more sustainable.

Researchers recreated conditions from billions of years ago and found that Earth’s young atmosphere could make key molecules linked to life. These sulfur-rich compounds, including certain amino acids, may have formed naturally in the sky. The results suggest early Earth wasn’t starting from zero but may have already been stocked with essential ingredients.

Ant pupae that are fatally sick don’t hide their condition; instead, they release a special scent that warns the rest of the colony. This signal prompts worker ants to open the pupae’s cocoons and disinfect them with formic acid, stopping the infection before it can spread. Although the treatment kills the sick pupa, it protects the colony and helps ensure its long-term survival. Researchers found that only pupae too sick to recover send this scent, showing just how finely tuned the colony’s early-warning system is.