Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping other immune cells fight longer and harder. The team discovered how to precisely control a key signal that determines which type of T cell forms. This advance could lead to ready-made cell therapies that are cheaper, faster, and easier to access.

Scientists have uncovered a surprising reason why some chronic wounds refuse to heal, even when treated with antibiotics. A common bacterium found in long-lasting wounds does not just resist drugs. It actively releases damaging molecules that overwhelm skin cells and stop them from repairing tissue. Researchers discovered that neutralizing these harmful molecules with antioxidants allows skin cells to recover and restart healing.

Scientists have uncovered new clues about why diabetic foot infections can become so severe and difficult to treat. By analyzing the DNA of E. coli bacteria taken from infected wounds around the world, researchers found an unexpected level of diversity, with many strains carrying genes linked to antibiotic resistance and aggressive disease. Rather than a single dangerous strain, multiple types of E. coli appear able to thrive in diabetic foot ulcers, helping explain why infections can worsen quickly and sometimes lead to amputation.

Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.

A nearby active galaxy called VV 340a offers a dramatic look at how a supermassive black hole can reshape its entire host. Astronomers observed a relatively weak but restless jet blasting outward from the galaxy’s core, wobbling like a spinning top as it plows through surrounding gas. Using a powerful mix of space- and ground-based telescopes, the team showed that this jet heats, ionizes, and flings gas out of the galaxy at a surprisingly high rate.

NASA’s Artemis II rocket has reached its launch pad after a painstaking overnight crawl across Kennedy Space Center. Engineers are now preparing for crucial fueling and countdown tests ahead of the first crewed Artemis mission. The mission will send four astronauts on a journey around the Moon and back. It’s a key milestone on the path to returning humans to the Moon and pushing onward to Mars.

Physicists have unveiled a new way to simulate a mysterious form of dark matter that can collide with itself but not with normal matter. This self-interacting dark matter may trigger a dramatic collapse inside dark matter halos, heating and densifying their cores in surprising ways. Until now, this crucial middle ground of behavior was nearly impossible to model accurately. The new code makes these simulations faster, more precise, and accessible enough to run on a laptop.

Scientists at Johns Hopkins have uncovered a surprising new way to influence brain activity by targeting a long-mysterious class of proteins linked to anxiety, schizophrenia, and movement disorders. Once thought to be mostly inactive, these proteins—called GluDs—turn out to play an active role in how brain cells communicate and form connections.

As global energy demand surges—driven by AI-hungry data centers, advanced manufacturing, and electrified transportation—researchers at the National Renewable Energy Laboratory have unveiled a breakthrough that could help squeeze far more power from existing electricity supplies. Their new silicon-carbide-based power module, called ULIS, packs dramatically more power into a smaller, lighter, and cheaper design while wasting far less energy in the process.

Long before humans became master hunters, our ancestors were already thriving by making the most of what nature left behind. New research suggests that scavenging animal carcasses wasn’t a desperate last resort, but a smart, reliable survival strategy that shaped human evolution. Carrion provided calorie-rich food with far less effort than hunting, especially during hard times, and humans were uniquely suited to take advantage of it—from strong stomach acid and long-distance walking to fire, tools, and teamwork.

Sensitive hearing may have evolved in mammal ancestors far earlier than scientists once believed. By modeling how sound moved through the skull of Thrinaxodon, a 250-million-year-old mammal predecessor, researchers found it likely used an early eardrum to hear airborne sounds. This challenges the long-held idea that these animals mainly “listened” through their jaws or bones. The results reveal that a key feature of modern mammal hearing was already taking shape deep in prehistory.

A deadly fungus that has wiped out hundreds of amphibian species worldwide may have started its global journey in Brazil. Genetic evidence and trade data suggest the fungus hitchhiked across the world via international frog meat markets. The findings raise urgent concerns about how wildlife trade can spread hidden biological threats.

A major new scientific review brings reassuring news for expectant parents: using acetaminophen, commonly known as Tylenol, during pregnancy does not increase a child’s risk of autism, ADHD, or intellectual disability. Researchers analyzed 43 high-quality studies, including powerful sibling comparisons that help separate medication effects from genetics and family environment. Earlier warnings appear to have been driven by underlying maternal health factors such as fever or pain rather than the medication itself.

Plastic-coated fertilizers used on farms are emerging as a major but hidden source of ocean microplastics. A new study found that only a tiny fraction reaches beaches through rivers, while direct drainage from fields to the sea sends far more plastic back onto shore. Once there, waves and tides briefly trap the particles on beaches before many vanish again. This helps explain why so much plastic pollution seems to disappear after reaching the ocean.

Researchers found that autistic and non-autistic people move their faces differently when expressing emotions like anger, happiness, and sadness. Autistic participants tended to rely on different facial features and produced more varied expressions, which can look unfamiliar to non-autistic observers. The study suggests emotional misunderstandings are a two-way street, not a one-sided deficit.

Cannabis-based medicines have been widely promoted as a potential answer for people living with chronic nerve pain—but a major new review finds the evidence just isn’t there yet. After analyzing more than 20 clinical trials involving over 2,100 adults, researchers found no strong proof that cannabis products outperform placebos in relieving neuropathic pain. Even when small improvements were reported, especially with THC-CBD combinations, they weren’t large enough to make a real difference in daily life.

Scientists have discovered that breast cancer can quietly throw the brain’s internal clock off balance—almost immediately after cancer begins. In mice, tumors flattened the natural daily rhythm of stress hormones, disrupting the brain-body feedback loop that regulates stress, sleep, and immunity. Remarkably, when researchers restored the correct day-night rhythm in specific brain neurons, stress hormone cycles snapped back into place, immune cells flooded the tumors, and the cancers shrank—without using any anti-cancer drugs.

While social media continues to circulate claims linking acetaminophen to autism in children, medical experts say those fears distract from a far more serious and proven danger: overdose. Acetaminophen, found in Tylenol and many cold and flu remedies, is one of the leading causes of emergency room visits, hospitalizations, and acute liver failure in the United States.

Solid-state batteries could store more energy and charge faster than today’s batteries, but they tend to crack and fail over time. Stanford researchers found that a nanoscale silver treatment can greatly strengthen the battery’s ceramic core. The silver helps seal tiny flaws and prevents lithium from causing further damage. This simple approach could help unlock next-generation batteries.

When scientists sent bacteria-infecting viruses to the International Space Station, the microbes did not behave the same way they do on Earth. In microgravity, infections still occurred, but both viruses and bacteria evolved differently over time. Genetic changes emerged that altered how viruses attach to bacteria and how bacteria defend themselves. The findings could help improve phage therapies against drug-resistant infections.