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Illuminating the twist: Light-driven inversion of supramolecular chirality

In a striking demonstration of molecular control, a team of scientists has harnessed light to reverse the twist in self-assembling molecules. The study identifies how trace residual aggregates in photo-responsive azobenzene solutions can reverse helical chirality through secondary nucleation. By using precise control of ultraviolet and visible light, the researchers could switch between the rotation of helices, offering a breakthrough for novel materials with tunable properties.

New strategy may enable cancer monitoring from blood tests alone

A new, error-corrected method for detecting cancer from blood samples is much more sensitive and accurate than prior methods and may be useful for monitoring disease status in patients following treatment, according to a new study. The method, based on whole-genome sequencing of DNA, also represents an important step toward the goal of routine blood test-based screening for early cancer detection.

Better tools when searching for genetic causes of asthma

A new study combines genetic data and improved computational tools to look more closely at GWAS results for both adult-onset and childhood-onset asthma. The research identified many genetic variants with a high likelihood of having a causal effect on both types of asthma, paving the way for further studies to target the genes connected to these variants as potential treatments.

The brain resorts to myelin when other brain nutrients are depleted

Marathon runners experience reversible changes in their brain myelin. These findings indicate that myelin (a substance that surrounds the neurons) exhibits behavior that was previously unknown, and that it contributes towards the brain's energy metabolism when other sources of energy are running low. Understanding how myelin in the runners recovers quickly may provide clues for developing treatments for demyelinating diseases such as multiple sclerosis.

A milestone for laser plasma acceleration

Laser plasma acceleration is a potentially disruptive technology: It could be used to build far more compact accelerators and open up new use cases in fundamental research, industry and health. However, on the path to real-world applications, some properties of the plasma-driven electron beam as delivered by current prototype accelerators still need to be refined. DESY's LUX experiment has now made significant progress in this direction: Using a clever correction system, a research team was able to significantly improve the quality of electron bunches accelerated by a laser plasma accelerator. This brings the technology a step closer to concrete applications, such as a plasma-based injector for a synchrotron storage ring.

How mothers adapt to the metabolic demands of nursing

Nursing poses major metabolic demands on mothers, to which they respond by eating more and saving energy to sustain milk production. There are significant hormonal changes during lactation, but how they lead to metabolic adaptations in nursing mothers remained unclear. Medical researchers uncovered a mechanism that connects prolactin, estrogen, the brain and metabolic adaptations during lactation.

Key brain networks behind post-stroke urinary incontinence identified

A new study using functional magnetic resonance imaging (fMRI) reveals the neural mechanisms that contribute to urinary incontinence, a common condition affecting stroke survivors that has a significant impact on their quality of life. The research was conducted by a multidisciplinary team of urologists, neurosurgeons, and imaging experts. The study utilized an innovative method of repeated bladder filling and voiding while participants were inside the MRI, during which their brain function was measured.
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