Low vitamin D levels may make recovery from breast cancer surgery more painful, according to a study of 184 women undergoing mastectomy. Patients with vitamin D deficiency were three times more likely to experience moderate to severe pain during the first 24 hours after surgery and also used substantially more of the opioid painkiller tramadol. They received slightly more fentanyl during surgery and experienced more postoperative nausea as well.

Ancient DNA reveals that plague was already killing hunter-gatherers in Siberia 5,500 years ago, long before cities and flea-driven epidemics. The prehistoric strains may have been especially dangerous because they carried a genetic factor capable of provoking severe immune reactions.

Cancer rates are rising in adults under 55, and new research suggests accelerated biological aging may be one piece of the puzzle. Scientists found that people from more recent generations tended to have bodies that appeared biologically older than those of earlier generations at the same chronological age. Greater biological age acceleration was linked to a higher risk of early onset cancers, with specific patterns seen for lung, gastrointestinal, uterine and colorectal cancers.

A foundational chemistry concept found in textbooks for almost 100 years may have been taught incorrectly. Researchers say the inductive effect in neutral molecules appears to extend only across one chemical bond, rather than gradually weakening over three or four bonds as traditionally taught. The team argues that updating this explanation could make organic chemistry easier to understand and provide a stronger foundation for future research and innovation.

More than 60 years after surveys suggested a deep coral reef off Benin was probably dead, scientists have found it alive. Cameras revealed healthy-looking coral patches supporting multiple fish species more than 50 meters beneath the surface. The discovery suggests West Africa’s coastal waters may contain other overlooked reefs that have yet to be documented.

Scientists have discovered that the brain’s short-range wiring may help protect cognition even as gray matter shrinks with age. Healthier connections just beneath the brain’s surface were linked to better language skills and appeared to weaken the impact of gray matter loss.

A World War I submarine wreck off Denmark is leaking TNT into the surrounding water, seabed, and marine life more than a century after it sank. Scientists warn that thousands of similar wrecks could pose growing environmental risks as they continue to corrode.

A wearable device has revealed nighttime hormone surges that may expose a frequently missed cause of high blood pressure. The discovery could help explain why primary aldosteronism often escapes standard blood tests and point toward a more accurate way to diagnose it.

Captive-raised saltwater crocodiles released into Bangladesh’s Sundarbans surprised scientists by settling into the wild rather than trying to return to their breeding facility. The result suggests that releasing larger, mature captive crocodiles could help restore depleted populations more successfully than relying only on vulnerable hatchlings.

Sucralose, the artificial sweetener used in Splenda, came under scrutiny after a study found that a related chemical damaged DNA and weakened the gut barrier in laboratory experiments. But later findings have complicated that alarming picture.

Mount Etna’s ancient eruptions followed radically different paths, with some magma lingering near the surface for weeks while other magma raced upward from nearly 30 kilometers deep in just hours. Scientists traced the difference to volcanic gases such as carbon dioxide and water, offering a powerful new way to understand and potentially anticipate explosive eruptions.

Scientists have found that Arctic cyclones become especially destructive when several strike one after another. These storm clusters cause about twice as much sea ice loss as isolated cyclones, with impacts that persist roughly two and a half times longer. As Arctic ice becomes thinner and weaker, the damage from these storms appears to be increasing, potentially creating a feedback loop that accelerates future ice loss.

Scientists discovered that aging cells can use malfunctioning mitochondria to unlock inflammatory genes and keep the immune system stuck in a prolonged state of alert. Blocking one part of this process reduced inflammation and improved healthy aging in mice, suggesting a promising new strategy for fighting age-related decline.

AI analysis of 400,000 Reddit posts found that users of drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound reported unexpected symptoms including menstrual changes, chills, hot flashes, and fatigue. Researchers cannot say the medications caused these problems, but the patterns may reveal overlooked signals worth studying.

Scientists found that the 3D organization of DNA is disrupted in several types of brain cells affected by Alzheimer’s disease, altering how important genes are switched on and off. The discovery reveals a previously underexplored layer of the disease that could open new paths for understanding and eventually treating Alzheimer’s.

A massive worldwide survey of physicists has revealed surprisingly little agreement about some of the universe’s biggest mysteries. No majority backed the standard cosmological model, a leading explanation for dark matter, or any single theory of quantum gravity. One area of stronger agreement stood out: 68% said the Big Bang does not necessarily represent the beginning of time. Researchers say the divisions show just how alive and unsettled the frontiers of physics remain.

Scientists are combining an electron microscope with a quantum computer to squeeze far more information from each electron. The approach could reveal faint details with fewer electrons, helping protect fragile samples that conventional microscopy can damage.

Scientists have engineered yeast to turn PET plastic and agricultural waste into ingredients for protein-rich, 3D-printed cookies called µBites. Developed partly for NASA’s Deep Space Food Challenge, the system can produce proteins, fats, vitamins, and even vanilla flavoring from waste materials. Researchers hope the unusual technology could eventually help address both plastic pollution and food insecurity, while also supplying food in extreme environments such as deep-space missions.

The Indian and Pacific oceans have been climatically linked for centuries, but scientists say that connection is now breaking down in an exceptional way. Ancient climate records suggest volcanoes disrupted the relationship in the past, while today human-caused warming appears to be driving a much more unusual shift.

Researchers have experimentally demonstrated the optical Magnus effect for the first time, revealing that a tightly focused laser interacts most strongly with an atom slightly away from the beam’s center. The unexpected shift is similar to the physics that makes a spinning table tennis ball curve through the air. Because lasers are used to control qubits, the effect could create errors in quantum computers, but it might also provide a new way to couple qubits together.