Researchers have created a method called optovolution that uses light to guide the evolution of proteins with dynamic behaviors. By engineering yeast cells so their survival depended on proteins switching states at the right time, scientists could rapidly select the best-performing variants. The technique produced new light-sensitive proteins that respond to different colors and improved optogenetic systems. It even evolved a protein that behaves like a tiny logic gate, activating genes only when two signals are present.

Global warming has picked up speed in the past decade, according to a new analysis from the Potsdam Institute for Climate Impact Research (PIK). By removing short term natural influences such as El Niño, volcanic eruptions, and solar cycles from temperature records, researchers uncovered a clear acceleration in the planet’s long term warming trend beginning around 2015.

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic fingerprint.” Some of the enzymes gather around damaged DNA to assist with repair. The discovery reveals an unexpected link between metabolism and gene regulation that could influence how cancers grow and respond to treatment.

Scientists have found a way to significantly boost “blue energy,” which generates electricity from the mixing of saltwater and freshwater. By coating nanopores with lipid molecules that create a friction-reducing water layer, they enabled ions to pass through much more efficiently while keeping the process highly selective. Their prototype membrane produced about two to three times more power than current technologies. The discovery could help bring osmotic energy closer to becoming a practical renewable power source.

Exercise normally boosts the body’s ability to use oxygen, a key marker of health and longevity — but high blood sugar can block that benefit. Researchers found that a ketogenic diet helped mice normalize blood sugar and dramatically improved how their muscles responded to exercise. Their muscles became better at using oxygen and built more endurance fibers. The results suggest diet and exercise may work together in surprising ways to improve metabolic health.

Pre-workout supplements promising extra energy for workouts may come with a hidden cost: severely reduced sleep. A study of people aged 16–30 found users were more than twice as likely to sleep five hours or less per night. Many of these products pack huge doses of caffeine and stimulants that can linger for hours. Researchers say the findings raise concerns about the impact on young people’s health and development.

A prehistoric mass grave in Serbia reveals that more than 77 people—mostly women and children—were deliberately killed in a brutal act of violence about 2,800 years ago. Genetic evidence suggests the victims came from different communities, indicating the massacre may have been a calculated message during fierce territorial struggles in Iron Age Europe.

DNA is revealing that many animals once thought to be a single species may actually be several hidden ones. But research on Bornean fanged frogs shows the line between species can be blurry—an important challenge when deciding what wildlife needs protection most.

Plants constantly juggle oxygen inside their cells, but scientists have now discovered a surprising twist in how that balance works. Researchers at the University of Helsinki found that mitochondria—the cell’s energy generators—can actively pull oxygen away from chloroplasts, the structures responsible for photosynthesis. This previously unknown interaction suggests mitochondria can effectively “drain” oxygen inside plant cells, altering photosynthesis and the production of reactive molecules that help plants respond to stress.

Astronomers have created the largest and most detailed 3D map yet of a glowing signal from the early universe, revealing hidden galaxies and gas from 9-11 billion years ago. By analyzing faint “Lyman-alpha” light emitted by energized hydrogen, scientists used an advanced technique called line intensity mapping to capture not just the brightest galaxies but also the vast cosmic structures surrounding them.

When NASA’s DART spacecraft deliberately crashed into the asteroid moonlet Dimorphos, it did more than change the asteroid’s local orbit — it slightly shifted the path of the entire asteroid pair around the Sun. The impact blasted debris into space, doubling the force of the spacecraft’s hit and nudging the system’s solar orbit by a tiny but measurable amount. It marks the first time humans have altered the trajectory of a celestial object around the Sun. The result strengthens the case for using spacecraft impacts as a future planetary defense strategy.

Physicists have long struggled to unite quantum mechanics—the theory governing tiny particles—with Einstein’s theory of gravity, which explains the behavior of stars, planets, and the structure of the universe. Researchers at TU Wien have now taken a new step toward that goal by rethinking one of relativity’s core ideas: the paths particles follow through curved spacetime, known as geodesics. By creating a quantum version of these paths—called the q-desic equation—the team showed that particles moving through a “quantum” spacetime may deviate slightly from the paths predicted by classical relativity.

Satellites are giving scientists a powerful new way to watch over the world’s bridges. Using radar imaging, researchers can detect millimeter-scale movements that may signal early structural problems long before inspectors notice them. The study found many bridges—especially in North America—are aging and increasingly vulnerable, but satellite monitoring could sharply reduce the number classified as high-risk. The approach could be especially valuable in regions where traditional monitoring barely exists.

A growing trend called “fibermaxxing” is putting dietary fiber in the spotlight—and for good reason. Fiber plays a powerful role in keeping the body healthy, from supporting digestion and feeding beneficial gut microbes to helping regulate blood sugar and cholesterol. Researchers say getting enough fiber may even lower the risk of conditions like obesity, diabetes, and certain cancers.

While exploring ancient seabeds in Morocco, scientists discovered strange wrinkle-like textures in deep-water sediments that shouldn’t have been there. These structures are usually made by sunlight-loving microbial mats in shallow waters. But the rocks formed far below the reach of light, suggesting a different explanation. Evidence points to chemosynthetic microbes—organisms powered by chemical reactions—creating the mats in the dark depths of an ancient ocean.

A massive UK study of more than 165,000 dementia patients has uncovered troubling new evidence about risperidone, a commonly used drug for severe agitation. Researchers found the antipsychotic increases stroke risk in dementia patients across the board—including those with no prior heart disease or stroke—challenging the long-held belief that some patients might be safer candidates than others. Because risperidone is the only drug of its type licensed for dementia, doctors often use it as a last resort when distressing symptoms become unmanageable.

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor that helps neurons communicate and found that ketamine reshapes its activity in specific brain regions tied to mood and reward. These shifts strongly matched improvements in patients’ symptoms. The findings could help scientists develop better ways to predict who will benefit from ketamine therapy.

Scientists are exploring a new way to harness the medical promise of psychedelic compounds without the mind-bending side effects. Researchers created modified versions of psilocin — the active form of psilocybin from “magic mushrooms” — that still target key serotonin pathways linked to depression and other brain disorders but appear to cause far fewer psychedelic-like effects.

Engineers have discovered an unexpected link between two very different realms of physics: the behavior of electrons in graphene and magnetic waves in specially engineered materials. By designing a thin magnetic film with a hexagonal pattern of holes—similar to graphene’s structure—the researchers showed that magnetic “spin waves” can follow the same mathematical rules as graphene’s famously unusual electrons. The surprising overlap reveals a deeper connection between electronic and magnetic systems and gives scientists a powerful new way to study complex magnetic materials.

A Yale study found that lowering parent stress can help protect young children from obesity. When parents practiced mindfulness and stress-management skills, their kids showed healthier eating patterns and avoided the weight gain seen in families that only focused on diet and exercise.