Artificial intelligence is now designing custom proteins in seconds—a process that once took years—paving the way for cures to diseases like cancer and antibiotic-resistant infections. Australian scientists have joined this biomedical frontier by creating bacteria-killing proteins with AI. Their new platform, built by a team of biologists and computer scientists, is part of a global movement to democratize and accelerate protein design for medical breakthroughs.

What if your brain is the reason some pain feels unbearable? Scientists at the Salk Institute have discovered a hidden brain circuit that gives pain its emotional punch—essentially transforming ordinary discomfort into lasting misery. This breakthrough sheds light on why some people suffer more intensely than others from conditions like fibromyalgia, migraines, and PTSD. By identifying the exact group of neurons that link physical pain to emotional suffering, the researchers may have found a new target for treating chronic pain—without relying on addictive medications.

Male guppies that glow with more orange aren’t just fashion-forward — they’re also significantly more sexually active. A UBC study reveals that brighter coloration is linked to virility and is genetically tied to brain development, suggesting a deeper evolutionary function. Researchers found that these bold hues aren't just for attracting mates, but are rooted in a vast, multi-chromosomal genetic system that enables tens of thousands of possible color pattern combinations. The work sheds light on how vibrant displays, behavior, and genetic fitness are intertwined in evolution.

What if humans didn’t have to suffer the slow-burning fire of chronic inflammation as we age? A surprising study on two types of lemurs found no evidence of "inflammaging," a phenomenon long assumed to be universal among primates. These findings suggest that age-related inflammation isn’t inevitable and that environmental factors could play a far bigger role than we thought. By peering into the biology of our primate cousins, researchers are opening up new possibilities for preventing aging-related diseases in humans.

A groundbreaking step in AI hardware efficiency comes from Germany, where scientists have engineered a vast spin waveguide network that processes information with far less energy. These spin waves quantum ripples in magnetic materials offer a promising alternative to power-hungry electronics.

MIT engineers have developed a tiny implantable device that could revolutionize emergency treatment for people with Type 1 diabetes. The device contains a powdered form of glucagon and can be remotely triggered—either manually or automatically by a glucose monitor—to release the hormone when blood sugar drops too low. This offers a potentially life-saving safety net, especially during sleep or for young children.

Imagine if you could "print" a tiny skyscraper using DNA instead of steel. That’s what researchers at Columbia and Brookhaven are doing—constructing intricate 3D nanostructures by harnessing the predictable folding of DNA strands. Their new design method uses voxel-like building blocks and an algorithm called MOSES to fabricate nanoscale devices in parallel, with applications ranging from optical computing to bio-scaffolds. Unlike traditional lithography or 3D printing, this self-assembly process occurs entirely in water and could revolutionize the future of nanomanufacturing.

Midlife sleep habits may matter more than previously thought. A large study finds that poor sleep, alongside high blood pressure and nicotine use, sharply increases the risk of heart problems in menopausal women yet only 1 in 5 score well on overall heart health.

Scientists at UCSF combined advanced brain-network modeling, genetics, and imaging to reveal how tau protein travels through neural highways and how certain genes either accelerate its toxic journey or shield brain regions from damage. Their extended Network Diffusion Model pinpoints four gene categories that govern vulnerability or resilience, reshaping our view of Alzheimer’s progression and spotlighting fresh therapeutic targets.

Climate change is silently sapping the nutrients from our food. A pioneering study finds that rising CO2 and higher temperatures are not only reshaping how crops grow but are also degrading their nutritional value especially in vital leafy greens like kale and spinach. This shift could spell trouble for global health, particularly in communities already facing nutritional stress. Researchers warn that while crops may grow faster, they may also become less nourishing, with fewer minerals, proteins, and antioxidants raising concerns about obesity, weakened immunity, and chronic diseases.

A laser-equipped research platform has, for the first time, photographed airflow just millimeters above ocean waves, revealing two simultaneous wind–wave energy-transfer tricks—slow short waves steal power from the breeze, while long giants sculpt the air in reverse. These crisp observations promise to overhaul climate and weather models by clarifying how heat, momentum, and greenhouse gases slip between sea and sky.

People can intuitively sense how biodiverse a forest is just by looking at photos or listening to sounds, and their gut feelings surprisingly line up with what scientists measure.

Long-tailed macaques given short videos were glued to scenes of fighting—especially when the combatants were monkeys they knew—mirroring the human draw to drama and familiar faces. Low-ranking individuals watched most intently, perhaps for self-protection, while high-strung ones averted their gaze.

Creatine isn’t just for gym buffs; Virginia Tech scientists are using focused ultrasound to sneak this vital energy molecule past the blood-brain barrier, hoping to reverse devastating creatine transporter deficiencies. By momentarily opening microscopic gateways, they aim to revive brain growth and function without damaging healthy tissue—an approach that could fast-track from lab benches to lifesaving treatments.

Losing weight isn’t always winning at health, say experts challenging the long-standing obsession with BMI and dieting. New evidence shows that most people with higher body weight can’t sustain long-term weight loss through lifestyle changes—and the pressure to do so may actually cause harm. From disordered eating to reinforced stigma, the consequences go beyond the physical. A growing movement urges doctors to shift away from the scale and toward personalized, compassionate care that values overall well-being, not just shrinking waistlines.

A groundbreaking collaboration between Los Alamos scientists and Duke University has resurrected a nearly forgotten 1938 experiment that may have quietly sparked the age of fusion energy. Arthur Ruhlig, a little-known physicist, first observed signs of deuterium-tritium (DT) fusion nearly a decade before its significance became clear in nuclear science. The modern team not only confirmed the essence of Ruhlig s original findings but also traced how his work may have inspired key Manhattan Project insights.

Astronomers have spotted centimeter-sized “pebbles” swirling around two infant stars 450 light-years away, revealing the raw ingredients of planets already stretching to Neptune-like orbits. Using the UK’s e-MERLIN radio array, the PEBBLeS project found these rocky seeds in unprecedented detail, bridging the elusive gap between dusty discs and fully-formed worlds. The discovery hints that systems even larger than our own could be commonplace and sets the stage for the upcoming Square Kilometre Array to map hundreds more planetary nurseries.

Astronomers using the Green Bank Telescope spotted surprisingly cold, dense hydrogen clouds embedded inside the Milky Way’s vast, super-hot Fermi bubbles—structures thought to be created by a recent, violent outburst from the galaxy’s core. Because such chilled gas should evaporate quickly in million-degree surroundings, its survival hints that the bubbles are only about a million years old. Ultraviolet data from Hubble backs the discovery, and the clouds’ million-mph speeds reinforce the bubbles’ youth. The find forces scientists to rethink how energy and matter flow through galaxies.

Scientists from UCL and the University of Cambridge have revealed that "space ice"—long thought to be completely disordered—is actually sprinkled with tiny crystals, changing our fundamental understanding of ice in the cosmos. These micro-crystals, just nanometers wide, were identified through simulations and lab experiments, revealing that even the most common ice in space retains a surprising structure. This has major implications not just for astrophysics, but also for theories about the origin of life and advanced materials technology.

In the remote reaches of Arizona s Petrified Forest National Park, scientists have unearthed North America's oldest known pterosaur a small, gull-sized flier that once soared above Triassic ecosystems. This exciting find, alongside ancient turtles and armored amphibians, sheds light on a key moment in Earth's history when older animal groups overlapped with evolutionary newcomers. The remarkably preserved fossils, including over 1,200 specimens, offer a rare glimpse into a vibrant world just before a mass extinction reshaped life on Earth.