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Scientists reveal the best exercise to ease knee arthritis pain

A sweeping review of over 200 studies finds that aerobic exercises like walking and cycling offer the best pain relief and mobility gains for knee osteoarthritis. Compared to other types of exercise, aerobic training showed the strongest evidence across short- and long-term outcomes. All forms of exercise were found to be safe, but experts recommend making aerobic activity the foundation of treatment.

Your DNA may shape how you use cannabis

A major collaboration between UC San Diego and 23andMe identified genes that shape cannabis use behaviors. The study linked the CADM2 and GRM3 genes to cannabis use and connected these patterns to more than 100 traits across mental and physical health. Researchers say understanding these genetic influences could help prevent cannabis use disorder and guide future therapies.

The hidden evolution making men’s sperm more dangerous with age

Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing revealed dozens of genes under selective pressure, many linked to serious disorders. The work reveals how evolution inside the testes can quietly shape the next generation’s genetic health.

Glowing sugars show how microbes eat the ocean's carbon

Researchers have developed a light-emitting sugar probe that exposes how marine microbes break down complex carbohydrates. The innovative fluorescent tool allows scientists to visualize when and where sugars are degraded in the ocean. This breakthrough helps map microbial activity and carbon cycling, providing new clues about how the ocean stores and releases carbon.

This powerful drug combo cuts prostate cancer deaths by 40%

A new drug combo of enzalutamide and hormone therapy has been shown to extend survival for men with recurring prostate cancer, reducing death risk by over 40%. The study followed more than 1,000 patients worldwide and was led by Cedars-Sinai researchers. Experts call it a game changer that’s likely to reshape treatment guidelines for aggressive prostate cancer.

Cancer patients who got a COVID vaccine lived much longer

A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t. Researchers from the University of Florida and MD Anderson Cancer Center discovered that the vaccine’s immune-activating properties may boost cancer-fighting responses, acting like a nonspecific “flare” that reawakens the immune system.

A clue to ancient life? What scientists found inside Mars’ frozen vortex

Mars’ north polar vortex locks its atmosphere in extreme cold and darkness, freezing out water vapor and triggering a dramatic rise in ozone. Scientists found that the lack of sunlight and moisture lets ozone build up unchecked. This discovery, made with data from ESA’s and NASA’s orbiters, could reveal clues about Mars’ past atmospheric chemistry and potential for life.

These 80-year-olds have the memory of 50-year-olds. Scientists finally know why

SuperAgers defy normal aging by keeping sharp memories and healthy brains well into their 80s. Northwestern scientists discovered that these individuals either resist the buildup of harmful brain proteins or remain unaffected by them. Their brains stay structurally youthful, and their strong social lives may help protect cognition. The findings could inspire new ways to delay or prevent dementia.

A hidden gene could triple wheat yields

Researchers discovered the gene that gives a rare wheat variety its unusual “triple-grain” trait. When switched on, the gene helps wheat flowers produce extra grain-bearing parts. The finding could allow scientists to grow new, high-yield crops to meet global food demand. It’s a simple genetic change with world-changing potential.

Einstein’s overlooked idea could explain how the Universe really began

Researchers have unveiled a new model for the universe’s birth that replaces cosmic inflation with gravitational waves as the driving force behind creation. Their simulations show that gravity and quantum mechanics may alone explain the structure of the cosmos. This elegant approach challenges traditional Big Bang interpretations and revives a century-old idea rooted in Einstein’s work.

Breakthrough cancer therapy stops tumor growth without harming healthy cells

Scientists have found a new way to stop cancer growth without damaging healthy cells. Researchers from the Francis Crick Institute and Vividion Therapeutics discovered a compound that blocks the signal telling cancer cells to grow and divide. The treatment worked in mice with lung and breast tumors and didn’t cause harmful side effects seen in earlier drugs. Now entering human trials, this breakthrough could open the door to safer, more precise cancer therapies.

Even “diet” soda may be quietly damaging your liver, scientists warn

Both regular and “diet” soft drinks may be far worse for liver health than believed. A massive study of over 120,000 participants found that consuming more than one can a day of either sugar-sweetened or low/no-sugar beverages sharply increased the risk of metabolic-associated steatotic liver disease (MASLD) and even liver-related deaths. Surprisingly, “diet” drinks carried similar or higher risks, potentially through changes in gut bacteria and appetite regulation.

Something mysterious is lighting up the Milky Way. Could it be dark matter?

Scientists at Johns Hopkins may be closing in on dark matter’s elusive trail, uncovering a mysterious gamma ray glow at the heart of our galaxy that could signal unseen matter colliding — or perhaps the frantic spin of dying stars. Using advanced simulations that account for the Milky Way’s ancient formation, researchers found a near-perfect match between theoretical and observed gamma ray maps, tightening the link between dark matter and this puzzling energy. Yet the mystery remains: could these signals come from millisecond pulsars instead?

How cutting lipids could starve breast cancer

Researchers found that triple-negative breast cancer cells are “addicted” to lipids, a feature tied to obesity. By studying mice, they discovered that high lipid levels alone accelerate tumor growth. Lowering these fats slowed cancer progression, suggesting that lipid-lowering treatments could help. The findings also caution against high-fat diets such as keto for patients with obesity.

Stanford scientists grow thousands of mini human brains using common food additive

Stanford scientists have solved a long-standing challenge in growing brain organoids by using a simple food additive to keep them from sticking together. The breakthrough enables the production of thousands of identical mini-brains at once, making large-scale testing and research possible. This leap could revolutionize how we study brain development and screen drugs for side effects. The discovery opens new paths to understanding and treating disorders such as autism and schizophrenia.

This common liver supplement could boost cancer treatment success

Salk Institute scientists discovered that bile acids in the liver can weaken immune cell function, making immunotherapy less effective against liver cancer. They pinpointed specific bile acids that suppress T cells and found that supplementing with UDCA reversed the effect, controlling tumor growth in mice. Since UDCA is already used for liver disease, it could quickly translate into clinical trials.
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