Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based cancer therapy. Helper T cells act as the immune system’s coordinators, helping other immune cells fight longer and harder. The team discovered how to precisely control a key signal that determines which type of T cell forms. This advance could lead to ready-made cell therapies that are cheaper, faster, and easier to access.

Scientists have uncovered a surprising reason why some chronic wounds refuse to heal, even when treated with antibiotics. A common bacterium found in long-lasting wounds does not just resist drugs. It actively releases damaging molecules that overwhelm skin cells and stop them from repairing tissue. Researchers discovered that neutralizing these harmful molecules with antioxidants allows skin cells to recover and restart healing.

Scientists have uncovered new clues about why diabetic foot infections can become so severe and difficult to treat. By analyzing the DNA of E. coli bacteria taken from infected wounds around the world, researchers found an unexpected level of diversity, with many strains carrying genes linked to antibiotic resistance and aggressive disease. Rather than a single dangerous strain, multiple types of E. coli appear able to thrive in diabetic foot ulcers, helping explain why infections can worsen quickly and sometimes lead to amputation.

Ibuprofen may be doing more than easing aches and pains—it could also help reduce the risk of some cancers. Studies have linked regular use to lower rates of endometrial and bowel cancer, likely because the drug dampens inflammation that fuels tumor growth. Researchers have even found it can interfere with genes cancer cells rely on to survive. Still, experts warn that long-term use carries risks and shouldn’t replace proven prevention strategies.

A nearby active galaxy called VV 340a offers a dramatic look at how a supermassive black hole can reshape its entire host. Astronomers observed a relatively weak but restless jet blasting outward from the galaxy’s core, wobbling like a spinning top as it plows through surrounding gas. Using a powerful mix of space- and ground-based telescopes, the team showed that this jet heats, ionizes, and flings gas out of the galaxy at a surprisingly high rate.

NASA’s Artemis II rocket has reached its launch pad after a painstaking overnight crawl across Kennedy Space Center. Engineers are now preparing for crucial fueling and countdown tests ahead of the first crewed Artemis mission. The mission will send four astronauts on a journey around the Moon and back. It’s a key milestone on the path to returning humans to the Moon and pushing onward to Mars.

Physicists have unveiled a new way to simulate a mysterious form of dark matter that can collide with itself but not with normal matter. This self-interacting dark matter may trigger a dramatic collapse inside dark matter halos, heating and densifying their cores in surprising ways. Until now, this crucial middle ground of behavior was nearly impossible to model accurately. The new code makes these simulations faster, more precise, and accessible enough to run on a laptop.

Scientists at Johns Hopkins have uncovered a surprising new way to influence brain activity by targeting a long-mysterious class of proteins linked to anxiety, schizophrenia, and movement disorders. Once thought to be mostly inactive, these proteins—called GluDs—turn out to play an active role in how brain cells communicate and form connections.

As global energy demand surges—driven by AI-hungry data centers, advanced manufacturing, and electrified transportation—researchers at the National Renewable Energy Laboratory have unveiled a breakthrough that could help squeeze far more power from existing electricity supplies. Their new silicon-carbide-based power module, called ULIS, packs dramatically more power into a smaller, lighter, and cheaper design while wasting far less energy in the process.

Long before humans became master hunters, our ancestors were already thriving by making the most of what nature left behind. New research suggests that scavenging animal carcasses wasn’t a desperate last resort, but a smart, reliable survival strategy that shaped human evolution. Carrion provided calorie-rich food with far less effort than hunting, especially during hard times, and humans were uniquely suited to take advantage of it—from strong stomach acid and long-distance walking to fire, tools, and teamwork.

Sensitive hearing may have evolved in mammal ancestors far earlier than scientists once believed. By modeling how sound moved through the skull of Thrinaxodon, a 250-million-year-old mammal predecessor, researchers found it likely used an early eardrum to hear airborne sounds. This challenges the long-held idea that these animals mainly “listened” through their jaws or bones. The results reveal that a key feature of modern mammal hearing was already taking shape deep in prehistory.

A deadly fungus that has wiped out hundreds of amphibian species worldwide may have started its global journey in Brazil. Genetic evidence and trade data suggest the fungus hitchhiked across the world via international frog meat markets. The findings raise urgent concerns about how wildlife trade can spread hidden biological threats.

A major new scientific review brings reassuring news for expectant parents: using acetaminophen, commonly known as Tylenol, during pregnancy does not increase a child’s risk of autism, ADHD, or intellectual disability. Researchers analyzed 43 high-quality studies, including powerful sibling comparisons that help separate medication effects from genetics and family environment. Earlier warnings appear to have been driven by underlying maternal health factors such as fever or pain rather than the medication itself.

Plastic-coated fertilizers used on farms are emerging as a major but hidden source of ocean microplastics. A new study found that only a tiny fraction reaches beaches through rivers, while direct drainage from fields to the sea sends far more plastic back onto shore. Once there, waves and tides briefly trap the particles on beaches before many vanish again. This helps explain why so much plastic pollution seems to disappear after reaching the ocean.

Researchers found that autistic and non-autistic people move their faces differently when expressing emotions like anger, happiness, and sadness. Autistic participants tended to rely on different facial features and produced more varied expressions, which can look unfamiliar to non-autistic observers. The study suggests emotional misunderstandings are a two-way street, not a one-sided deficit.

Cannabis-based medicines have been widely promoted as a potential answer for people living with chronic nerve pain—but a major new review finds the evidence just isn’t there yet. After analyzing more than 20 clinical trials involving over 2,100 adults, researchers found no strong proof that cannabis products outperform placebos in relieving neuropathic pain. Even when small improvements were reported, especially with THC-CBD combinations, they weren’t large enough to make a real difference in daily life.

Scientists have discovered that breast cancer can quietly throw the brain’s internal clock off balance—almost immediately after cancer begins. In mice, tumors flattened the natural daily rhythm of stress hormones, disrupting the brain-body feedback loop that regulates stress, sleep, and immunity. Remarkably, when researchers restored the correct day-night rhythm in specific brain neurons, stress hormone cycles snapped back into place, immune cells flooded the tumors, and the cancers shrank—without using any anti-cancer drugs.

Mercedes-Benz’s decision to offer an all-electric version of the G-Class hasn’t come without controversy. After all, one of the most iconic and traditionally rugged off-roaders can now glide along in complete silence.

Still, fresh off a strong 2025 for the G-Wagen lineup in America, Mercedes is moving ahead with its electrification strategy, now aiming to boost interest in the G580 with EQ Technology.

Read: Mercedes’ Electric G Flops So Hard It Could Change What Comes Next

The electric G-Class is currently offered with a $10,000 Incentive Bonus, now available whether you lease or buy the vehicle outright. Previously, this discount was capped at $5,000 and applied only to lease agreements, according to Cars Direct.

Whether that’s enough to sway potential buyers is another matter entirely.

The G580 starts at $164,550 including destination. However, as is often the case, finding one at base MSRP is nearly impossible. A quick search on Cars.com turned up 224 listings, with only a single example priced at MSRP. Most hovered between $180,000 and $190,000.

Even so, at base price, a $10,000 discount, while not insignificant, doesn’t sound like it will do much to tip the scales. It amounts to roughly 6 percent off, and for typical G-Class buyers, that might equate to a minor financial blip, not a reason to commit.

Sales Flop

Mercedes recently confirmed it delivered 49,700 G-Class vehicles globally last year, a 23 percent jump over the previous year and a new high-water mark for the model. What it didn’t share is how many of those were the electric G580 and how many still carried internal combustion.

However, reports from early last year described the G580 as a sales “flop,” noting that just 1,450 examples had been sold in Europe as of April 2025, and only 58 in China. It was also claimed that Mercedes had failed to sell a single example in the US, though that was never officially confirmed.

Porsche and boats have been flirting for a while. The German sports car brand already helped create a rapid electric speedboat with Austrian builder Frauscher. Now the partnership is back with a smaller boat called the 790 Spectre and a one-off, marine-inspired Macan concept to keep it company.

No, the Macan Turbo Concept Lago can’t jump from the road to water like a Gibbs Aquada or Amphicar 770. But it borrows some neat nautical design and trim ideas in the same way that the Frauscher’s boats have cribbed the Macan’s motors and battery pack. And it has some of the most stylish floor mats we’ve ever seen.

Related: Alfa’s Yacht-Winged Giulia Quadrifoglio Special Is Fast, Wild, And Already Sold Out

Porsche raided its Exclusive Manufaktur personalisation catalog and roped in experts from its Sonderwunsch “special wish” department to give the concept a distinctly salty vibe.

Darkteal Metallic paint, which originates from Porsche’s Paint to Sample programme, covers the outside while neat graphics tie the car to the matching boat. Even the keys wear the same color.

Swab the Floor Mats, Matey

Open the doors and the nautical theme gets stronger. Real wood inspired by boat decks lines the front and rear luggage compartments and the floor mats look ready for bare feet.

A compass replaces the usual dashboard stopwatch and the seat centers use marine grade fabric trimmed with Crayon leather. Green contrast stitching finishes the look and proves Porsche’s trim specialists can customise almost anything.

Frauscher 790 Spectre

The Concept Lago is just a one-off, unlike the new Frauscher 790 Spectre it’s designed to promote. Engineers built the 7,970 mm (313.8 inches) sports boat around the same 100 kWh battery and dual electric motor setup used in the Macan Turbo, though Porsche quotes 630 hp (639 PS / 470 kW) for the SUV and 536 hp (544 PS / 400 kW) for its sea-going counterpart.

The hull is new and lighter than before and the cockpit borrows plenty of Porsche style touches, including the steering wheel and elements of the seat design. Buyers can personalise the boat with special paint and materials to mirror their car.

Orders for the 790 Spectre are open now, but the price is going to make a $112,700 Macan Turbo Electric look downright affordable. While neither Porsche or Frauscher has indicated an exact sticker, the fact that the earlier 850 Fantom Air cost around $600k tells us this one is for wealthy Porsche and boat lovers only.

Porsche

It appears you can add Mazda to the growing list of automakers that have delayed electric vehicles in the wake of lower than expected demand. According to reports out of Japan, the company’s first dedicated EV has been pushed back until at least 2029.

Details are still murky, but Autonews cites Nikkei and Nikkan Jidosha as saying that production has been delayed by at least two years. Instead, the company will reportedly turn its attention to more popular hybrids.

More: Mazda’s New EV Caught Testing In America

While a spokesperson said Mazda hasn’t officially announced anything, they didn’t exactly deny the reports either. Quite the opposite, as in a statement to Autonews, they said, “We continue to advance the technological development of our proprietary BEVs based on our multi-solution strategy, and will determine the timing of their introduction while carefully assessing regulatory trends in each country and changes in customer needs.”

This suggests launch plans are still up in the air and could slip beyond 2027.

Test Mule Raises Questions

Baldauf

This is an interesting development as spy photographers snapped a mule undergoing testing in California late last year. The model wore a heavily modified CX-70 or CX-90 body and featured a fully enclosed grille as well as blocked off air curtains. The vehicle was said to be roughly the same size as the CX-50, but narrower than the body suggested.

Little is known about the EV at this point, but it’s slated to ride on the Skyactiv EV Scalable Architecture. The platform was originally announced in 2021 and was supposed to be introduced last year.

That obviously didn’t happen and it appears plans to introduce several vehicles on the architecture between 2025 and 2030 are also in jeopardy. These were set to include “various vehicle sizes and body types.”

However, the situation has changed significantly in the past few years. In the United States alone, the Trump administration has enacted steep new tariffs and eliminated the clean vehicle tax credit. The latter has caused a significant drop in EV sales and a rethink by many automakers.

Nevertheless, Mazda isn’t giving up on electric vehicles as the company recently introduced the CX-6e in Europe. It’s a Chinese collaboration with joint-venture partner Changan, and the model has a lot in common with the Deepal S07.